Trichodysplasia spinulosa: A rare complication of immunosuppression
نویسندگان
چکیده
TS: trichodysplasia spinulosa TSPyV: TS-associated polyoma virus INTRODUCTION Trichodysplasia spinulosa (TS) is a recently described rare disease of immunosuppressed patients characterized by folliculocentric papules and keratin spicules. The condition is highly associated with the TS-associated polyomavirus (TSPyV); however, the causal mechanism remains undiscovered. Currently, there is a dearth of case reports on this condition, and treatment for TS is not well established. We report a case of TS that successfully responded to reduction of immunosuppression.
منابع مشابه
Two cases of trichodysplasia spinulosa responsive to compounded topical cidofovir 3% cream.
TS: trichodysplasia spinulosa TSPyV: trichodysplasia spinulosa polyomavirus INTRODUCTION Solid organ transplant patients are susceptible to rare and unusual dermatoses as a result of their chronic immunosuppression. Trichodysplasia spinulosa (TS) is one such rare clinical entity observed predominantly in immunosuppressed patients with a history of either solid organ transplantation on immunosup...
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We identified a new polyomavirus in skin lesions from a patient with trichodysplasia spinulosa (TS). Apart from TS being an extremely rare disease, little is known of its epidemiology. On the basis of knowledge regarding other polyomaviruses, we anticipated that infections with trichodysplasia spinulosa-associated polyomavirus (TSV) occur frequently and become symptomatic only in immunocompromi...
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The trichodysplasia-spinulosa polyomavirus-associated (TSPyV) was first described in a solid organ transplant recipient with a rare skin disease. Initially mistaken as a side effect of cyclosporine treatment, the disease trichodysplasia-spinulosa (TS) is characterized by the development of keratin spines (spicules), follicular papules, hair follicle dilation and keratotic plugging of the infund...
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IMPORTANCE The cause of follicular spicules in multiple myeloma (MM) is not known. OBSERVATIONS We present a case of follicular spicules in a patient with MM, which is very reminiscent of trichodysplasia spinulosa caused by a polyomavirus. No trichodysplasia spinulosa-associated polyomavirus could be isolated from the skin lesions; however, the spicules were positive for Merkel cell carcinoma...
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عنوان ژورنال:
دوره 2 شماره
صفحات -
تاریخ انتشار 2016